There are a few locations within the Registry where String (REG_SZ) values or 32-bit REG_DWORD values can be set to disable either all or some of the Windows Key shortcuts.
If you'd like to reset these locations to rule out that as a possibility then:
Download the attached Reset Windows Key Shortcuts.reg file
Before using scan with your security software to ensure there is no malware/virus issues
When satisfied the download is safe, right-click and select merge
You'll be prompted by the User Account Control; click Yes
You'll next be prompted by the Registry to confirm you want to add information; click Yes
Finally, the Registry Editor Information alert will inform you the additions were made; click OK
Right-click your Taskbar and select Task Manager
Scroll to bottom of Task Manager and right-click on Windows Explorer and select Restart
Your screen will momentarily darken/flash. This is normal.
Close Task Manager
Done!
For those curious the following Registry locations may contain the aforementioned String values:
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