Have you considered upgrading to the latest version of the Software to see if it behaved any better.
Personally, I would be very cautious about using any such program that was suppose to "TuneUp" my computer, but even more so, one that was not designed specifically for Windows 10 and was exhibiting problems every time I ran it.
I don't think I would want that mucking about with my Operating System nor would I feel comfortable and confident if I had to make concessions to standard settings just to get it to run.