You mean the change to Windows 11?
From MS Docs site.
For the best Windows 11 upgrade experience, eligible devices should be running Windows 10, version 20H1 or later.
S mode is only supported on the Home edition of Windows 11. If you are running a different edition of Windows in S mode, you will need to first switch out of S mode
prior to upgrading.
Switching a device out of Windows 10 in S mode also requires internet connectivity. If you switch out of S mode, you cannot switch back to S mode later.
It seems to say that if the machine can run W11 and is already in S mode it will be fine.