Why would you do that?? Do you mean permanently or just once??
the "run as administrator" option has system wide privileges and I am talking about root privileges which opens every door on your system for malware.
Unless I did not quite get what you mean....
I agree, some programs need those privileges to run properly but this will only be on demand and in certain situations. If you want to run an app with admin privileges, you can right click on the Icon and click on [run as administrator]. Not all apps have this option, only app which are needed to run the system....