I'm having the same issue with 10 pro following the upgrade from 7 pro. ie sleep mode locks everything up doesn't give access to the login screen and causes the nessesity for a reboot often with the prelogin screen & screensplash screen hanging. If the system is shut down fast boot works fine and the next power up is pretty quick
Tried running the power troubleshooter, resetting advanced power scheme and different power button options and tried switching to the native power scheme, as opposed to the manufacturers all to no avail. Pretty sure this is the problem - ie a hardware compatibility/driver power issues with login and waking up, but being as Fujitsu haven't even released their desk update tool for easy BIOS driver updating - that's compatible with 10 - I'm reluctant to start changing drivers just yet. Switching users also causes similar issues ie no access to login, as does logging off as a user. Powering down gives access to both users at logon with no problems.
I'm pretty sure this was a big issue during beta testing and prerelease - and MS issued specific updates to deal with it...
Being as the fast boot is working so well - about 30 seconds from power on to desktop, - I've pretty much disabled sleep and will just turn it off at night, till either Microsoft or Fujitsu release a fix.
So far everything else is working without a problem and the upgrade worked pretty much unattended. Which has got to be a first for MS. It even kept themes and desktop layouts and settings for all users and takes up less room on the disk.